Inappropriate Antibiotic Use in Soft Tissue Infections

Inappropriate antibiotic use in soft tissue infections.

HYPOTHESIS Many soft tissue infections treated with surgical drainage resolve even when treated with antibiotics not active against the organism isolated from the infection. DESIGN Retrospective. SETTING Integrated Soft Tissue Infection Services clinic. PATIENTS All patients treated from July 19, 2000, to August 1, 2001, who underwent surgical drainage of a soft tissue infection and had m...

Empirical antibiotics use in soft tissue infections.

PURPOSE Various antibiotics are available to treat soft-tissue infections. However, it is unclear if the empirical antibiotic is always appropriate or the most economical. OBJECTIVE To determine the percentage of empirically treated wounds susceptible to the antibiotic therapy prescribed, and to determine the percentage of wounds treated with the most economical antibiotic therapy. METHODS ...

Necrotizing Soft Tissue Infections

EVIDENCE DEFINITIONS · Class I: Prospective randomized controlled trial. · Class II: Prospective clinical study or retrospective analysis of reliable data. Includes observational, cohort, prevalence, or case control studies. · Class III: Retrospective study. Includes database or registry reviews, large series of case reports, expert opinion. · Technology assessment: A technology study which doe...

Necrotizing Soft-Tissue Infections

151 Necrotizing soft-tissue infections have been recognized for centuries. Hippocrates vividly described the disease in the 5th century BC, as follows: ÒThe erysipelas would quickly spread in all directions. Flesh, sinews, and bones fell away in great quantities.Ó Necrotizing soft-tissue infections were subsequently designated as Òstreptococcal gangrene,Ó Òphagedena,Ó and Òphagedena gangrenosum...

Necrotizing Soft Tissue Infections.